What is CIRCADIN?
CIRCADIN is the original prolonged release melatonin and has demonstrated positive effects on sleep quality, quality of life, and most importantly next day alertness and functioning in people with insomnia.‡
‡Studies compared to placebo in adults aged 55 years and over.
CIRCADIN is indicated for the short-term treatment of primary insomnia* characterised by poor sleep quality, in adults aged 55 or older.
*Primary insomnia is insomnia without an underlying medical cause or any other clear cause.
CIRCADIN is available from your pharmacy with or without a prescription.
Ask your pharmacist – they will advise if CIRCADIN is right for you.
How does CIRCADIN work?
Not all melatonin products are the same.
CIRCADIN’s prolonged release formulation has been developed to mimic the natural release of our body’s own melatonin, to restore healthy sleep.
It means that after you take the tablet, which should be swallowed whole 1 to 2 hours before your chosen bedtime, the active ingredient (melatonin) is gradually released and absorbed by your body over 8-10 hours throughout the night, reproducing the body’s natural melatonin secretion cycle – which is less during the day and more at night.
CIRCADIN works by gradually releasing melatonin to increase your natural tendency to sleepiness and promote refreshing sleep – just as the release of natural melatonin produced by your body does.
How and when do I take CIRCADIN?
Swallow your tablet whole with a full glass of water – DO NOT crush, chew or divide your tablet as CIRCADIN tablets have been specially designed to gradually release melatonin while you sleep.
If you crush, chew or divide the tablet it will not work properly.
Take ONE tablet at the same time each day
1-2 hours before bedtime
FAQs
It depends. A 3-week supply of Circadin can be obtained without a prescription for people aged 55 or older. However, you will need to talk to your pharmacist first so they can decide if it’s right for you. Otherwise, you should speak to your doctor.
The sleep promoting effect of Circadin will take place from 1 to 2 hours after taking a tablet.
For the best effect, take Circadin as directed. (Circadin should be used regularly at the same time each day, after food and 1 to 2 hours before you go to bed). To approach your sleep issues holistically, we recommend you also follow good sleep hygiene practices.
Always speak to your doctor or pharmacist if you are unsure.
Circadin has a specific, prolonged release formulation which means the melatonin is slowly released over the course of 8 to 10 hours and mimics the body’s natural pattern of melatonin release.1
Circadin is a pharmaceutical grade melatonin product – which means it has been carefully assessed for quality, efficacy and consistency, and has been approved for use in Australia.
Circadin is best taken after eating and 1 to 2 hours before your selected bedtime. Ideally, it should be taken at approximately the same time each day.
We are here to help you sleep better
What is CIRCADIN used for?
CIRCADIN is indicated for the short-term treatment of primary insomnia* characterised by poor quality of sleep, in adults aged 55 or older.
*Primary insomnia is insomnia without an underlying medical cause or any other clear cause.
Sleep problems
Everyone struggles with sleep occasionally, but if it keeps happening then seeking advice is the healthy thing to do.
¥Wade AG, et al. Curr Med Res Opin. 2007; 23(10):2597-2605; supported by Neurim.
References
- CIRCADIN® Consumer Medicine Information (CMI).
- Wade AG, et al. BMC Medicine. 2010;8:51. Funded by Neurim Pharmaceuticals, Tel Aviv, Israel.
- Wade AG, et al. Curr Med Res Opin. 2007;23(10):2597-2605. Funded by Neurim Pharmaceuticals, Tel Aviv, Israel.
- Zisapel N. Open Neuroendocrinology J. 2010;3:85-95.
- Luthringer R, et al. Int Clin Psychopharmacol. 2009;24:239-249. Sponsored by Neurim Pharmaceuticals, Tel Aviv, Israel.
- Haimov I, et al. Sleep. 1995;18(7):598-603. Funded by Neurim Pharmaceuticals, Tel Aviv, Israel.
- CIRCADIN® Product Information. Last amended 11 November 2020.
- Lemoine P, et al. J Sleep Res. 2007;16:372-380. Sponsored by Neurim Pharmaceuticals, Tel Aviv, Israel.
- Arendt J, Skene DJ. Sleep Med Rev. 2005;9:25-39. Sponsored by Neurim Pharmaceuticals, Tel Aviv, Israel.
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